Difference between revisions of "RapC"
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase | |style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[ComA]] activity |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 5.024 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 5.024 | ||
| Line 52: | Line 52: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' control of [[ComA]] activity {{PubMed|12950917}} |
* '''Protein family:''' RAP family (according to Swiss-Prot) | * '''Protein family:''' RAP family (according to Swiss-Prot) | ||
| Line 68: | Line 68: | ||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| − | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' binding of [[PhrC]] to [[RapC]] prevents it from binding [[ComA]] {{PubMed|12950917}} |
| − | * '''Interactions:''' [[RapC]]-[[PhrC]], [[RapC]]-[[ComA]] | + | * '''Interactions:''' [[RapC]]-[[PhrC]] {{PubMed|12950917}}, [[RapC]]-[[ComA]] {{PubMed|12950917}} |
* '''Localization:''' | * '''Localization:''' | ||
Revision as of 08:03, 29 November 2009
- Description: response regulator aspartate phosphatase
| Gene name | rapC |
| Synonyms | yclL |
| Essential | no |
| Product | response regulator aspartate phosphatase |
| Function | control of ComA activity |
| MW, pI | 45 kDa, 5.024 |
| Gene length, protein length | 1146 bp, 382 aa |
| Immediate neighbours | yclK, phrC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU03770
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: RAP family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Localization:
Database entries
- Structure:
- UniProt: P94415
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Leighton Core, Marta Perego
TPR-mediated interaction of RapC with ComA inhibits response regulator-DNA binding for competence development in Bacillus subtilis.
Mol Microbiol: 2003, 49(6);1509-22
[PubMed:12950917]
[WorldCat.org]
[DOI]
(P p)
B A Lazazzera, I G Kurtser, R S McQuade, A D Grossman
An autoregulatory circuit affecting peptide signaling in Bacillus subtilis.
J Bacteriol: 1999, 181(17);5193-200
[PubMed:10464187]
[WorldCat.org]
[DOI]
(P p)
