Difference between revisions of "RbsK"
| Line 89: | Line 89: | ||
=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''[[rbsR]]-[[rbsK]]-[[rbsD]]-[[rbsA]]-[[rbsC]]-[[rbsB]]'' {{PubMed|7921236}} | ||
| − | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|7511775}} | |
| − | |||
| − | * '''[[Sigma factor]]:''' [[SigA]] | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** repressed by glucose ([[CcpA]]) {{PubMed|7921236}} | ||
** expressed upon transition into the stationary phase ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7592460 PubMed] | ** expressed upon transition into the stationary phase ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7592460 PubMed] | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[CcpA]]: transcription repression {{PubMed|7921236}} | ||
** [[AbrB]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/7592460 PubMed] | ** [[AbrB]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/7592460 PubMed] | ||
| Line 122: | Line 123: | ||
=References= | =References= | ||
| − | <pubmed>16872404,,7592460,7921236, </pubmed> | + | <pubmed>16872404,7511775,7592460,7921236, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:04, 9 January 2010
- Description: ribokinase
| Gene name | rbsK |
| Synonyms | |
| Essential | no |
| Product | ribokinase |
| Function | ribose utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 30 kDa, 4.61 |
| Gene length, protein length | 879 bp, 293 aa |
| Immediate neighbours | rbsR, rbsD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU35920
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + D-ribose = ADP + D-ribose 5-phosphate (according to Swiss-Prot)
- Protein family: carbohydrate kinase pfkB family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P36945
- KEGG entry: [3]
- E.C. number: 2.7.1.15
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Le Thi Tam, Christine Eymann, Dirk Albrecht, Rabea Sietmann, Frieder Schauer, Michael Hecker, Haike Antelmann
Differential gene expression in response to phenol and catechol reveals different metabolic activities for the degradation of aromatic compounds in Bacillus subtilis.
Environ Microbiol: 2006, 8(8);1408-27
[PubMed:16872404]
[WorldCat.org]
[DOI]
(P p)
M A Strauch
AbrB modulates expression and catabolite repression of a Bacillus subtilis ribose transport operon.
J Bacteriol: 1995, 177(23);6727-31
[PubMed:7592460]
[WorldCat.org]
[DOI]
(P p)
K Woodson, K M Devine
Analysis of a ribose transport operon from Bacillus subtilis.
Microbiology (Reading): 1994, 140 ( Pt 8);1829-38
[PubMed:7921236]
[WorldCat.org]
[DOI]
(P p)
M O'Reilly, K Woodson, B C Dowds, K M Devine
The citrulline biosynthetic operon, argC-F, and a ribose transport operon, rbs, from Bacillus subtilis are negatively regulated by Spo0A.
Mol Microbiol: 1994, 11(1);87-98
[PubMed:7511775]
[WorldCat.org]
[DOI]
(P p)
