CydA

• Description: cytochrome bd ubiquinol oxidase (subunit I), high affinity terminal oxidase
  
  

Gene name	cydA
Synonyms	yxkK
Essential	no
Product	cytochrome bd ubiquinol oxidase (subunit I), high affinity terminal oxidase
Function	respiration
MW, pI	52 kDa, 8.935
Gene length, protein length	1404 bp, 468 aa
Immediate neighbours	cydB, cimH
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU38760

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

respiration, membrane proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Ubiquinol-8 + O₂ = Ubiquinone-8 + H₂O (according to Swiss-Prot)

• Protein family:

• Paralogous protein(s): YthA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s): contains an iron-sulfur cluster

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P94364

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: cydA-cydB-cydC-cydD PubMed

• Sigma factor:

• Regulation:
  • repressed by glucose (CcpA)
  • induced under anaerobic conditions (Rex) PubMed
  • expressed under anaerobic conditions (ResD) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression
  • Rex: transcription repression PubMed
  • ResD: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: