PssA

• Description: phosphatidylserine synthase
  
  

Gene name	pssA
Synonyms	pss
Essential	no
Product	phosphatidylserine synthase
Function	biosynthesis of phospholipids
Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis
MW, pI	19 kDa, 7.881
Gene length, protein length	531 bp, 177 aa
Immediate neighbours	ybfK, ybfM
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

biosynthesis of lipids, cell envelope stress proteins (controlled by SigM, W, X, Y), membrane proteins

This gene is a member of the following regulons

SigX regulon

The gene

Basic information

• Locus tag: BSU02270

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: CDP-diacylglycerol + L-serine = CMP + (3-sn-phosphatidyl)-L-serine (according to Swiss-Prot)

• Protein family: CDP-alcohol phosphatidyltransferase class-I family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane at the septum PubMed

Database entries

• Structure:

• UniProt: P39823

• KEGG entry: [3]

• E.C. number: 2.7.8.8

Expression and regulation

• Operon: pssA-ybfM-psd PubMed

• Sigma factor: SigA PubMed, SigX PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

K Matsumoto
Phosphatidylserine synthase from bacteria.
Biochim Biophys Acta: 1997, 1348(1-2);214-27
[PubMed:9370336] [WorldCat.org] [DOI] (P p)