Difference between revisions of "SipU"

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* '''Description:''' signal peptidase I <br/><br/>
  
 
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|style="background:#ABCDEF;" align="center"|'''Function''' || protein secretion
 
|style="background:#ABCDEF;" align="center"|'''Function''' || protein secretion
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU04010 sipU]
 
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]'''
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|colspan="2" | '''Genetic context''' <br/> [[Image:sipU_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:sipU_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sipU_454029_454592_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:sipU_expression.png|500px]]
 
 
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* '''Operon:''' ''sipU'' (according to [http://dbtbs.hgc.jp/COG/prom/sipU.html DBTBS])
 
* '''Operon:''' ''sipU'' (according to [http://dbtbs.hgc.jp/COG/prom/sipU.html DBTBS])
  
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sipU_454029_454592_1 sipU] {{PubMed|22383849}}
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* '''[[Sigma factor]]:'''  
 
 
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* '''Regulation:'''  
 
* '''Regulation:'''  

Revision as of 11:17, 7 August 2012

  • Description: signal peptidase I

Gene name sipU
Synonyms ycsB
Essential no
Product signal peptidase I
Function protein secretion
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 21 kDa, 9.844
Gene length, protein length 561 bp, 187 aa
Immediate neighbours ycsA, yczH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SipU context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

protein secretion, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU04010

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins (according to Swiss-Prot)
  • Protein family: peptidase S26 family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: sipU (according to DBTBS)
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Jan Maarten van Dijl, Groningen, Netherlands

Your additional remarks

References