MrpB

• Description: Na+/H+ antiporter subunit, multiple resistance and pH homeostasis
  
  

Gene name	mrpB
Synonyms	yufU
Essential	yes PubMed
Product	Na+/H+ antiporter subunit
Function	sodium export
Gene expression levels in SubtiExpress: mrpB
Interactions involving this protein in SubtInteract: MprB
MW, pI	15 kDa, 4.912
Gene length, protein length	429 bp, 143 aa
Immediate neighbours	mrpA, mrpC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), essential genes, membrane proteins

The gene

Basic information

• Locus tag: BSU31610

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • MrpA-MrpB-MrpC-MrpD-MrpE-MrpF-MrpG (complex)

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O05259

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: mrpA-mrpB-mrpC-mrpD-mrpE-mrpF-mrpG PubMed

• Expression browser: mrpB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • SM-GN9 (mrpB-spc), available in Anne Galinier's and Boris Görke's labs

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: