Difference between revisions of "SdpC"

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|style="background:#ABCDEF;" align="center"|'''Function''' || killing of non-sporulating sister cells
 
|style="background:#ABCDEF;" align="center"|'''Function''' || killing of non-sporulating sister cells
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU33770 sdpC]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33770 sdpC]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SdpC SdpC]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SdpC SdpC]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sdpB]]'', ''[[sdpI]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sdpB]]'', ''[[sdpI]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15382&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU33770 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU33770 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU33770 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yvaY_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yvaY_context.gif]]

Revision as of 13:51, 13 May 2013

  • Description: toxin, collapses the proton motive force and induces autolysis, kills non-sporulating cells, induces activity of SigW

Gene name sdpC
Synonyms yvaY
Essential no
Product toxin, kills non-sporulating cells
Function killing of non-sporulating sister cells
Gene expression levels in SubtiExpress: sdpC
Interactions involving this protein in SubtInteract: SdpC
MW, pI 22 kDa, 9.611
Gene length, protein length 609 bp, 203 aa
Immediate neighbours sdpB, sdpI
Sequences Protein DNA Advanced_DNA
Genetic context
YvaY context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SdpC expression.png
























Categories containing this gene/protein

toxins, antitoxins and immunity against toxins

This gene is a member of the following regulons

AbrB regulon, Rok regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU33770

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • toxin, collapses the proton motive force and induces autolysis PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: the meture SDP is a 42-residue peptide with one disulfide bridge PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Additional information:
    • the amount of the mRNA is substantially decreased upon depletion of RNase Y PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original Publications

Additional publications: PubMed

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947