Difference between revisions of "GlpX"

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|style="background:#ABCDEF;" align="center"|'''Function''' || gluconeogenesis
 
|style="background:#ABCDEF;" align="center"|'''Function''' || gluconeogenesis
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU37090 glpX]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU37090 glpX]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism], [http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism], [http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]'''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rho]]'', ''[[murAB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rho]]'', ''[[murAB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15726&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU37090 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU37090 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU37090 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ywjI_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ywjI_context.gif]]

Revision as of 14:05, 13 May 2013

  • Description: class II fructose-1,6-bisphosphatase, gluconeogenesis

Gene name glpX
Synonyms ywjI
Essential no
Product class II fructose-1,6-bisphosphatase
Function gluconeogenesis
Gene expression levels in SubtiExpress: glpX
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism, Sugar catabolism
MW, pI 33 kDa, 5.067
Gene length, protein length 963 bp, 321 aa
Immediate neighbours rho, murAB
Sequences Protein DNA Advanced_DNA
Genetic context
YwjI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GlpX expression.png




























Categories containing this gene/protein

carbon core metabolism

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU37090

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-fructose 1,6-bisphosphate ==> D-fructose 6-phosphate + Pi
  • Protein family: FBPase class 2 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information: K(M) for FBP: 20 µM PubMed
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3D1R (from E. coli, 49% identity, 68% similarity)PubMed
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: constitutive PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References