Difference between revisions of "RpsR"

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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
 
* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
 +
** [[RpsF]]-[[RpsR]], the heterodimer binds the structure in the ''[[rpsF]]'' mRNA 5' UTR {{PubMed|24310371}}
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
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=Expression and regulation=
 
=Expression and regulation=
* '''Operon:''' ''[[yyaF]]-[[rpsF]]-[[ssbA]]-[[rpsR]]'' {{PubMed|14762004}}
+
* '''Operon:'''  
 +
** ''[[yyaF]]-[[rpsF]]-[[ssbA]]-[[rpsR]]'' {{PubMed|14762004}}
 +
** ''[[rpsF]]-[[ssbA]]-[[rpsR]]'' {{PubMed|24310371,22383849}}
  
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rpsR_4198603_4198842_-1 rpsR] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rpsR_4198603_4198842_-1 rpsR] {{PubMed|22383849}}
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
 +
** ''[[rpsF]]'': [[SigA]] {{PubMed|24310371}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
  
* '''Additional information:'''  the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
+
* '''Additional information:'''   
 +
** the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
 +
** the mRNA contains a structured motif in the 5' UTR upstream of the ''[[rpsF]]'' ORF that is bound by [[RpsF]]-[[RpsR]] heterodimers and may be implicated in autogenous regulation {{PubMed|24310371}}
 +
 
  
 
=Biological materials =
 
=Biological materials =
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=References=
 
=References=
<pubmed>12884008,14762004 ,11948146  19653700 11948165 23002217</pubmed>
+
<pubmed>12884008,14762004 ,11948146  19653700 11948165 23002217 22383849 24310371 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 18:30, 13 December 2013

Gene name rpsR
Synonyms
Essential yes PubMed
Product ribosomal protein S18
Function translation
Gene expression levels in SubtiExpress: rpsR
Interactions involving this protein in SubtInteract: RpsR
MW, pI 8 kDa, 11.494
Gene length, protein length 237 bp, 79 aa
Immediate neighbours exoA, ssbA
Sequences Protein DNA DNA_with_flanks
Genetic context
RpsR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RpsR expression.png















Categories containing this gene/protein

translation, essential genes

This gene is a member of the following regulons

ComK regulon, stringent response

The gene

Basic information

  • Locus tag: BSU40890

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
    • ComK: transcription activation PubMed
  • Regulatory mechanism:
  • Additional information:
    • the mRNA is very stable (half-life > 15 min) PubMed
    • the mRNA contains a structured motif in the 5' UTR upstream of the rpsF ORF that is bound by RpsF-RpsR heterodimers and may be implicated in autogenous regulation PubMed


Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References