Difference between revisions of "OxdC"

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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
 
** phosphorylated on Arg-12 {{PubMed|22517742}}
 
** phosphorylated on Arg-12 {{PubMed|22517742}}
  
* '''Cofactor(s):''' requires Mn(II) for activity [http://www.ncbi.nlm.nih.gov/sites/entrez/19473032 PubMed]
+
* '''[[Cofactors]]:'''  
 +
** requires two Mn(II) centers for activity {{PubMed|24444454,19473032}}
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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<pubmed>20464388 </pubmed>
 
<pubmed>20464388 </pubmed>
 
==Original publications==
 
==Original publications==
<pubmed>12056897,18573182,17269748,14871895 ,10960116 , 19047353, 19473032  11546787 15583401 21264418 21782782 22404040 23734819 21277974 22517742</pubmed>
+
<pubmed>12056897,18573182,17269748,14871895 ,10960116 , 19047353, 19473032  11546787 15583401 21264418 21782782 22404040 23734819 21277974 22517742 24444454 </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 18:18, 22 January 2014

  • Description: oxalate decarboxylase

Gene name oxdC
Synonyms yvrK
Essential no
Product oxalate decarboxylase
Function unknown
Gene expression levels in SubtiExpress: oxdC
MW, pI 43 kDa, 5.101
Gene length, protein length 1155 bp, 385 aa
Immediate neighbours yvrJ, yvrL
Sequences Protein DNA DNA_with_flanks
Genetic context
OxdC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
OxdC expression.png















Categories containing this gene/protein

acid stress proteins (controlled by YvrI-YvrHa), phosphoproteins

This gene is a member of the following regulons

YvrI-YvrHa regulon

The gene

Basic information

  • Locus tag: BSU33240

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Oxalate = formate + CO2 (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s): OxdD

Extended information on the protein

  • Kinetic information:
  • Modification:
    • phosphorylated on Arg-12 PubMed
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation: induced by acidic growth conditions PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

Your additional remarks

References

Reviews

Miia R Mäkelä, Kristiina Hildén, Taina K Lundell
Oxalate decarboxylase: biotechnological update and prevalence of the enzyme in filamentous fungi.
Appl Microbiol Biotechnol: 2010, 87(3);801-14
[PubMed:20464388] [WorldCat.org] [DOI] (I p)

Original publications