Difference between revisions of "TenA"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU11650&redirect=T BSU11650] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/tenAI-goxB-thiSGF-yjbV.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/tenAI-goxB-thiSGF-yjbV.html] | ||
| Line 88: | Line 89: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU11650&redirect=T BSU11650] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1YAF 1YAF], [http://www.rcsb.org/pdb/explore.do?structureId=2QCX 2QCX] (complex with formyl aminommethyl pyrimidine) | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1YAF 1YAF], [http://www.rcsb.org/pdb/explore.do?structureId=2QCX 2QCX] (complex with formyl aminommethyl pyrimidine) | ||
Revision as of 13:25, 2 April 2014
- Description: thiaminase II
| Gene name | tenA |
| Synonyms | |
| Essential | no |
| Product | thiaminase II |
| Function | thiamine salvage |
| Gene expression levels in SubtiExpress: tenA | |
| Metabolic function and regulation of this protein in SubtiPathways: tenA | |
| MW, pI | 27 kDa, 4.99 |
| Gene length, protein length | 708 bp, 236 aa |
| Immediate neighbours | yjbQ, tenI |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis of cofactors, most abundant proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU11650
Phenotypes of a mutant
Database entries
- BsubCyc: BSU11650
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Thiamine + H2O = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole (according to Swiss-Prot)
- Protein family: thiaminase-2 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- BsubCyc: BSU11650
- UniProt: P25052
- KEGG entry: [3]
- E.C. number: 3.5.99.2
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
- belongs to the 100 most abundant proteins PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
T P Begley, D M Downs, S E Ealick, F W McLafferty, A P Van Loon, S Taylor, N Campobasso, H J Chiu, C Kinsland, J J Reddick, J Xi
Thiamin biosynthesis in prokaryotes.
Arch Microbiol: 1999, 171(5);293-300
[PubMed:10382260]
[WorldCat.org]
[DOI]
(P p)
Original publications
