SdpR

• Description: transcriptional repressor of the sdpR-sdpI operon
  
  

Gene name	sdpR
Synonyms	yvbA
Essential	no
Product	transcriptional regulator (ArsR family)
Function	regulation of protection against SdpC
Gene expression levels in SubtiExpress: sdpR
Interactions involving this protein in SubtInteract: SdpR
MW, pI	10 kDa, 7.328
Gene length, protein length	270 bp, 90 aa
Immediate neighbours	sdpI, opuCD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, toxins, antitoxins and immunity against toxins

This gene is a member of the following regulons

AbrB regulon, SdpR regulon

The SdpR regulon:

• fadM-fadN-fadA-fadE, sdpR-sdpI

The gene

Basic information

• Locus tag: BSU33790

Database entries

• BsubCyc: BSU33790

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: SdpI binds and sequesters SdpR if extracellular SdpC is present, this results in induction of the sdpR-sdpI operon PubMed

• Interactions:
  • SdpI-SdpR PubMed

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU33790

• Structure:

• UniProt: O32242

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sdpR-sdpI PubMed

• Expression browser: sdpR PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed during logrithmic growth (AbrB) PubMed
  • induced by extracellular SdpC (SdpR) PubMed

• Regulatory mechanism:
  • AbrB: transcription repression PubMed
  • SdpR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: