Difference between revisions of "DesR"
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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of cold shock expression of des | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of cold shock expression of des | ||
|- | |- | ||
− | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/ | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19200 desR] |
+ | |- | ||
+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=DesR DesR] | ||
+ | |- | ||
+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=desR desR]''' | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 4.885 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 4.885 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[desK]]'', ''[[yocH]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[desK]]'', ''[[yocH]]'' | ||
|- | |- | ||
− | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU19200 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU19200 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU19200 DNA_with_flanks] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yocG_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yocG_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
+ | |- | ||
+ | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=desR_2091705_2092304_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:desR_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19200]] | ||
|- | |- | ||
|} | |} | ||
__TOC__ | __TOC__ | ||
− | + | <br/><br/><br/><br/> | |
− | <br/><br/><br/><br/><br/><br/> | + | <br/><br/><br/><br/> |
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/> | ||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
− | + | =The [[DesR regulon]]:= | |
+ | * ''[[des]]'' | ||
=The gene= | =The gene= | ||
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=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU19200&redirect=T BSU19200] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yocFG.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yocFG.html] | ||
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=== Additional information=== | === Additional information=== | ||
− | |||
− | |||
− | |||
=The protein= | =The protein= | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
− | * '''Interactions:''' [[DesK]]-[[DesR]] | + | * '''[[SubtInteract|Interactions]]:''' |
+ | ** [[DesK]]-[[DesR]] | ||
− | * '''Localization:''' cell membrane (according to Swiss-Prot) | + | * '''[[Localization]]:''' cell membrane (according to Swiss-Prot) |
=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU19200&redirect=T BSU19200] | ||
* '''Structure:''' | * '''Structure:''' | ||
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* '''Operon:''' ''[[desK]]-[[desR]]'' {{PubMed|11285232}} | * '''Operon:''' ''[[desK]]-[[desR]]'' {{PubMed|11285232}} | ||
+ | |||
+ | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=desR_2091705_2092304_1 desR] {{PubMed|22383849}} | ||
* '''Sigma factor:''' | * '''Sigma factor:''' | ||
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=References= | =References= | ||
− | <pubmed>10094672,12399512, 19595746, 11285232, 17087771 12207704</pubmed> | + | <pubmed>10094672,12399512, 19595746, 11285232, 17087771 12207704 25406381 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Latest revision as of 07:02, 24 November 2014
- Description: two-component response regulator, regulation of cold shock expression of des
Gene name | desR |
Synonyms | yocG |
Essential | no |
Product | two-component response regulator |
Function | regulation of cold shock expression of des |
Gene expression levels in SubtiExpress: desR | |
Interactions involving this protein in SubtInteract: DesR | |
Metabolic function and regulation of this protein in SubtiPathways: desR | |
MW, pI | 22 kDa, 4.885 |
Gene length, protein length | 597 bp, 199 aa |
Immediate neighbours | desK, yocH |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
lipid metabolism/ other, transcription factors and their control, cold stress proteins, membrane proteins, phosphoproteins
This gene is a member of the following regulons
The DesR regulon:
The gene
Basic information
- Locus tag: BSU19200
Phenotypes of a mutant
Database entries
- BsubCyc: BSU19200
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription activation of the des operon when phosphorylated by DesK
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylated by DesK on an Asp residue
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- BsubCyc: BSU19200
- Structure:
- UniProt: O34723
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- induced by cold shock (18-fold) PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Diego de Mendoza, Universidad Nacional de Rosario, Argentine homepage
Your additional remarks
References