Difference between revisions of "RNases"
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| − | RNases are involved in the processing and degradation of the different classes of mRNAs, tRNAs, rRNAs and [[small RNAs]] | + | ===RNases are involved in the processing and degradation of the different classes of mRNAs, tRNAs, rRNAs and [[small RNAs]]=== |
| + | {{CategoryTree | ||
| + | |Parents= | ||
| + | * 3. [[Information processing]] | ||
| + | ** 3.2. [[RNA synthesis and degradation]] | ||
| + | |Neighbours= | ||
| + | * 3.2.1. [[Transcription]] | ||
| + | * 3.2.2. [[RNA chaperones]] | ||
| + | * 3.2.3. [[DEAD-box RNA helicases]] | ||
| + | * 3.2.4. [[RNases]] | ||
| + | |Related= | ||
| + | [[RNA degradosome]] | ||
| + | |}} | ||
| + | |||
| + | __TOC__ | ||
| + | <br><br><br> | ||
| + | |||
| + | |||
| + | ==Exoribonucleases== | ||
| + | * [[rnjA|RNase J1]]: 5'-3' activity | ||
| + | |||
| + | * [[rph|RNase PH]]: 3'-5' activity | ||
| + | * [[YhaM]]: 3'-5' activity | ||
| + | * [[rnr|RNase R]]: 3'-5' activity | ||
| + | * [[pnpA|polynucleotide phosphorylase]]: 3'-5' activity | ||
| + | |||
| + | * [[nrnA|nano-RNase A]]: degrades oligonucleotides | ||
| + | * [[nrnB|nano-RNase B]]: degrades oligonucleotides | ||
| + | |||
| + | ==Endoribonucleases== | ||
| + | * [[rny|RNase Y]]: ssRNA endonuclease | ||
| + | * [[rnpA|RNase P]]: ssRNA endonuclease | ||
| + | * [[rnz|RNase Z]]: ssRNA endonuclease | ||
| + | * [[ndoA|RNase Endo A]] | ||
| + | * [[rnhB|RNase HII]]: cleaves RNA in RNA-DNA hybrids | ||
| + | * [[rnhC|RNase HIII]]: cleaves RNA in RNA-DNA hybrids | ||
| + | * [[yurI|RNase Bsn]]: extracellular RNase | ||
| + | * [[rnc|RNase III]]: dsRNA endonuclease | ||
| + | * [[mrnC|mini-III]]: dsRNA endonuclease | ||
| + | * [[rnmV|RNase M5]]: dsRNA endonuclease | ||
| + | |||
| + | == RNA pyrophosphohydrolase == | ||
| + | * [[RppH]] | ||
| + | |||
| + | ==Unknown activity== | ||
| + | * [[rnjB|RNase J2]]: similar to and interacting with [[rnjA|RNase J1]], but does not seem to have an own RNase activity | ||
| + | * [[YpdQ]]: similar to RNase HI | ||
| + | * [[YrrK]]: processing of the 5' end of pre-[[16S rRNA]] | ||
| + | * [[YqfG]]: putative endoribonuclease, important for rRNA maturation | ||
| + | |||
| + | ==Labs working on RNases== | ||
| + | * [[David Bechhofer]] | ||
| + | * [[Ciaran Condon]] | ||
| + | * [[Harald Putzer]] | ||
| + | * [[Jörg Stülke]] | ||
| + | |||
| + | ==Key original publications== | ||
| + | <pubmed> 12884008 22537947 25099370 </pubmed> | ||
| + | |||
| + | ==Reviews on RNases in ''Bacillus subtilis''== | ||
| + | <pubmed>21334965 19767421 21976285 22550495 19215774 12794188 12490701 20659169 23403287,21957024 22568516 24064983 25292357 25878039</pubmed> | ||
| + | |||
| + | =Back to [[categories]]= | ||
Latest revision as of 10:25, 2 January 2017
RNases are involved in the processing and degradation of the different classes of mRNAs, tRNAs, rRNAs and small RNAs
| Parent categories | |
| Neighbouring categories |
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| Related categories | |
Contents
- 1 RNases are involved in the processing and degradation of the different classes of mRNAs, tRNAs, rRNAs and small RNAs
- 2 Exoribonucleases
- 3 Endoribonucleases
- 4 RNA pyrophosphohydrolase
- 5 Unknown activity
- 6 Labs working on RNases
- 7 Key original publications
- 8 Reviews on RNases in Bacillus subtilis
- 9 Back to categories
Exoribonucleases
- RNase J1: 5'-3' activity
- RNase PH: 3'-5' activity
- YhaM: 3'-5' activity
- RNase R: 3'-5' activity
- polynucleotide phosphorylase: 3'-5' activity
- nano-RNase A: degrades oligonucleotides
- nano-RNase B: degrades oligonucleotides
Endoribonucleases
- RNase Y: ssRNA endonuclease
- RNase P: ssRNA endonuclease
- RNase Z: ssRNA endonuclease
- RNase Endo A
- RNase HII: cleaves RNA in RNA-DNA hybrids
- RNase HIII: cleaves RNA in RNA-DNA hybrids
- RNase Bsn: extracellular RNase
- RNase III: dsRNA endonuclease
- mini-III: dsRNA endonuclease
- RNase M5: dsRNA endonuclease
RNA pyrophosphohydrolase
Unknown activity
- RNase J2: similar to and interacting with RNase J1, but does not seem to have an own RNase activity
- YpdQ: similar to RNase HI
- YrrK: processing of the 5' end of pre-16S rRNA
- YqfG: putative endoribonuclease, important for rRNA maturation
Labs working on RNases
Key original publications
Bo Liu, Gintaras Deikus, Anna Bree, Sylvain Durand, Daniel B Kearns, David H Bechhofer
Global analysis of mRNA decay intermediates in Bacillus subtilis wild-type and polynucleotide phosphorylase-deletion strains.
Mol Microbiol: 2014, 94(1);41-55
[PubMed:25099370]
[WorldCat.org]
[DOI]
(I p)
Simen M Kristoffersen, Chad Haase, M Ryan Weil, Karla D Passalacqua, Faheem Niazi, Stephen K Hutchison, Brian Desany, Anne-Brit Kolstø, Nicolas J Tourasse, Timothy D Read, Ole Andreas Økstad
Global mRNA decay analysis at single nucleotide resolution reveals segmental and positional degradation patterns in a Gram-positive bacterium.
Genome Biol: 2012, 13(4);R30
[PubMed:22537947]
[WorldCat.org]
[DOI]
(I e)
G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008]
[WorldCat.org]
[DOI]
(P p)
Reviews on RNases in Bacillus subtilis
