Difference between revisions of "EfeO"

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m (Jstuelk moved page YwbM to EfeO: 23764491)
 
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* '''Description:''' elemental iron uptake system (permease) <br/><br/>
+
* '''Description:''' lipoprotein, elemental iron uptake system (binding protein), high affinity uptake of ferric iron (Fe(III))  <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || elemental iron uptake system (permease)  
+
|style="background:#ABCDEF;" align="center"| '''Product''' || elemental iron uptake system (binding protein)  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || iron uptake
+
|style="background:#ABCDEF;" align="center"|'''Function''' || elemental iron uptake
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38270 ywbM]
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38270 efeO]
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/YwbM YwbM]
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/EfeO EfeO]
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]'''
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=EfeO EfeO]'''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 4.712   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 4.712   
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1155 bp, 385 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1155 bp, 385 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywbN]]'', ''[[ywbL]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[efeB]]'', ''[[efeU]]''
 
|-
 
|-
 
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU38270 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU38270 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU38270 DNA_with_flanks]
 
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU38270 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU38270 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU38270 DNA_with_flanks]
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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
 +
** binds ferric iron (Fe(III)) with strong selectivity {{PubMed|23764491}}
  
 
* '''Protein family:''' UPF0409 family (according to Swiss-Prot)
 
* '''Protein family:''' UPF0409 family (according to Swiss-Prot)
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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
** ([[YwbL]]-[[YwbM]])-[[YwbN]] {{PubMed|23180473}}
+
** [[EfeO]]-[[EfeU]]-[[EfeB]] {{PubMed|23180473,23764491}}
  
 
* '''[[Localization]]:'''  
 
* '''[[Localization]]:'''  
 
** membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
 
** membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
 
+
** extracytosolic lipoprotein {{PubMed|23764491}}
 
=== Database entries ===
 
=== Database entries ===
  
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=Expression and regulation=
 
=Expression and regulation=
 
* '''Operon:'''  
 
* '''Operon:'''  
** ''[[ywbL]]-[[ywbM]]-[[ywbN]]'' {{PubMed|9353933}}
+
** ''[[efeU]]-[[efeO]]-[[efeB]]'' {{PubMed|9353933}}
  
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=efeM_3927951_3929108_-1 ywbM] {{PubMed|22383849}}
+
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=efeM_3927951_3929108_-1 efeO] {{PubMed|22383849}}
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|23764491}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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* '''Additional information:'''
 
* '''Additional information:'''
 +
** number of protein molecules per cell (minimal medium with glucose and ammonium): 1047 {{PubMed|24696501}}
 +
** number of protein molecules per cell (complex medium with amino acids, without glucose): 2113 {{PubMed|24696501}}
  
 
=Biological materials =
 
=Biological materials =
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=References=
 
=References=
  
<pubmed>16672620,9353933,12354229,18763711, 23180473</pubmed>
+
<pubmed>16672620,9353933,12354229,18763711, 23180473 23764491</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Latest revision as of 11:24, 17 April 2014

  • Description: lipoprotein, elemental iron uptake system (binding protein), high affinity uptake of ferric iron (Fe(III))

Gene name ywbM
Synonyms ipa-28d
Essential no
Product elemental iron uptake system (binding protein)
Function elemental iron uptake
Gene expression levels in SubtiExpress: efeO
Interactions involving this protein in SubtInteract: EfeO
Metabolic function and regulation of this protein in SubtiPathways:
EfeO
MW, pI 42 kDa, 4.712
Gene length, protein length 1155 bp, 385 aa
Immediate neighbours efeB, efeU
Sequences Protein DNA DNA_with_flanks
Genetic context
YwbM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YwbM expression.png















Categories containing this gene/protein

transporters/ other, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

  • Locus tag: BSU38270

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • binds ferric iron (Fe(III)) with strong selectivity PubMed
  • Protein family: UPF0409 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 1047 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 2113 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References