Difference between revisions of "EfeO"
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− | * '''Description:''' elemental iron uptake system ( | + | * '''Description:''' lipoprotein, elemental iron uptake system (binding protein), high affinity uptake of ferric iron (Fe(III)) <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Product''' || elemental iron uptake system ( | + | |style="background:#ABCDEF;" align="center"| '''Product''' || elemental iron uptake system (binding protein) |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"|'''Function''' || iron uptake | + | |style="background:#ABCDEF;" align="center"|'''Function''' || elemental iron uptake |
|- | |- | ||
− | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38270 | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38270 efeO] |
|- | |- | ||
− | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/EfeO EfeO] |
|- | |- | ||
− | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/ | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=EfeO EfeO]''' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 4.712 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 4.712 | ||
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1155 bp, 385 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1155 bp, 385 aa | ||
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[efeB]]'', ''[[efeU]]'' |
|- | |- | ||
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU38270 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU38270 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU38270 DNA_with_flanks] | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU38270 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU38270 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU38270 DNA_with_flanks] | ||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
+ | ** binds ferric iron (Fe(III)) with strong selectivity {{PubMed|23764491}} | ||
* '''Protein family:''' UPF0409 family (according to Swiss-Prot) | * '''Protein family:''' UPF0409 family (according to Swiss-Prot) | ||
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* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
− | ** | + | ** [[EfeO]]-[[EfeU]]-[[EfeB]] {{PubMed|23180473,23764491}} |
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
** membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed] | ** membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed] | ||
− | + | ** extracytosolic lipoprotein {{PubMed|23764491}} | |
=== Database entries === | === Database entries === | ||
Line 111: | Line 112: | ||
=Expression and regulation= | =Expression and regulation= | ||
* '''Operon:''' | * '''Operon:''' | ||
− | ** ''[[ | + | ** ''[[efeU]]-[[efeO]]-[[efeB]]'' {{PubMed|9353933}} |
− | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=efeM_3927951_3929108_-1 | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=efeM_3927951_3929108_-1 efeO] {{PubMed|22383849}} |
− | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|23764491}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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* '''Additional information:''' | * '''Additional information:''' | ||
+ | ** number of protein molecules per cell (minimal medium with glucose and ammonium): 1047 {{PubMed|24696501}} | ||
+ | ** number of protein molecules per cell (complex medium with amino acids, without glucose): 2113 {{PubMed|24696501}} | ||
=Biological materials = | =Biological materials = | ||
Line 145: | Line 148: | ||
=References= | =References= | ||
− | <pubmed>16672620,9353933,12354229,18763711, 23180473</pubmed> | + | <pubmed>16672620,9353933,12354229,18763711, 23180473 23764491</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Latest revision as of 11:24, 17 April 2014
- Description: lipoprotein, elemental iron uptake system (binding protein), high affinity uptake of ferric iron (Fe(III))
Gene name | ywbM |
Synonyms | ipa-28d |
Essential | no |
Product | elemental iron uptake system (binding protein) |
Function | elemental iron uptake |
Gene expression levels in SubtiExpress: efeO | |
Interactions involving this protein in SubtInteract: EfeO | |
Metabolic function and regulation of this protein in SubtiPathways: EfeO | |
MW, pI | 42 kDa, 4.712 |
Gene length, protein length | 1155 bp, 385 aa |
Immediate neighbours | efeB, efeU |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
transporters/ other, acquisition of iron, iron metabolism, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU38270
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- binds ferric iron (Fe(III)) with strong selectivity PubMed
- Protein family: UPF0409 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P39596
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References