hisF
168
imidazole glycerol phosphate synthase (synthase subunit)
Locus
BSU_34870
Molecular weight
27.14 kDa
Isoelectric point
5.24
Function
biosynthesis of histidine
Product
imidazole glycerol phosphate synthase (synthase subunit)
Essential
no
Synonyms
hisF
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0107 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,583,562 3,584,320
The protein
Catalyzed reaction/ biological activity
5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho--D-ribosyl)imidazole-4-carboxamide + L-glutamine --> 5-amino-1-(5-phospho--D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H+ + L-glutamate (according to UniProt)
Protein family
HisA/HisF family (with HisA, according to UniProt)
Structure
Paralogous protein(s)
cytoplasm (according to Swiss-Prot)
Additional information
belongs to the 100 most abundant proteins PubMed
Expression and Regulation
Operons
Biological materials
Mutant
References
Reviews
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Original Publications
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Time of last update: 2024-12-11 08:31:06
Author of last update: Melvin.boenninger