YidC2

• Description: Sec-independent membrane protein translocase
  
  

Gene name	yqjG
Synonyms
Essential	no
Product	Sec-independent membrane protein translocase
Function	membrane insertion of proteins and protein secretion
MW, pI	30 kDa, 9.903
Gene length, protein length	825 bp, 275 aa
Immediate neighbours	mifM, yqjF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU23890

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

protein secretion, membrane proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: Type 2 subfamily (according to Swiss-Prot)

• Paralogous protein(s): SpoIIIJ, one of the two proteins has to be present for viability PubMed

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P54544

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yqjG (according to DBTBS)

• Sigma factor:

• Regulation:
  • repressed by large amounts of SpoIIIJ, induced by small amounts of SpoIIIJ (MifM) PubMed

• Regulatory mechanism:
  • MifM: "attenuation mechanism", an mRNA hairpin of the yqjG transcript unfold upon translation arrest of MifM at decreased SpoIIIJ levels PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: