Difference between revisions of "AbrB"
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* '''Effectors of protein activity:''' interaction with [[AbbA]] results in inactivation of AbrB [http://www.ncbi.nlm.nih.gov/sites/entrez/18840696 PubMed] | * '''Effectors of protein activity:''' interaction with [[AbbA]] results in inactivation of AbrB [http://www.ncbi.nlm.nih.gov/sites/entrez/18840696 PubMed] | ||
| − | * '''Interactions:''' [[AbrB]]-[[AbbA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/18840696 PubMed] | + | * '''Interactions:''' [[AbrB]]-[[AbbA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/18840696 PubMed]; [[AbrB]]-[[AbrB]] {{PubMed|20817675}}, [[AbrB]]-[[Abh]] {{PubMed|20817675}} |
* '''Localization:''' | * '''Localization:''' | ||
| Line 135: | Line 135: | ||
=References= | =References= | ||
==Reviews== | ==Reviews== | ||
| − | <pubmed>11964117 19995980 11931565 </pubmed> | + | <pubmed>11964117 19995980 11931565 20817675 </pubmed> |
| − | |||
==Original Publications== | ==Original Publications== | ||
<pubmed> 19581368 ,3145384,2437099,8878039,2504584, 11377867,1850083,2106683,12586407, 12076816,17660417, 2554317,18430133,7768874, 2507867, 1766371, 15687200,1908787,18840696,2106683,15687200, 2504584,18840696 3145384 8821944 8576231 11101897 11395475 11583849 11751836 12123659 12076816 12591885 15610005 16223496 16159768 16702211 17660417 17720793 7592460, 19465659 20509597 </pubmed> | <pubmed> 19581368 ,3145384,2437099,8878039,2504584, 11377867,1850083,2106683,12586407, 12076816,17660417, 2554317,18430133,7768874, 2507867, 1766371, 15687200,1908787,18840696,2106683,15687200, 2504584,18840696 3145384 8821944 8576231 11101897 11395475 11583849 11751836 12123659 12076816 12591885 15610005 16223496 16159768 16702211 17660417 17720793 7592460, 19465659 20509597 </pubmed> | ||
Other publications: {{PubMed|19202088,18326573}} | Other publications: {{PubMed|19202088,18326573}} | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 18:29, 15 September 2010
- Description: transcriptional regulator of transition state genes
| Gene name | abrB |
| Synonyms | cpsX, tolB |
| Essential | no |
| Product | transcriptional regulator |
| Function | regulation of gene expression during the transition from growth to stationary phase |
| Metabolic function and regulation of this protein in SubtiPathways: Biofilm, His, Asp, Asn, Ammonium/ glutamate, Central C-metabolism, Sugar catabolism | |
| MW, pI | 10 kDa, 6.57 |
| Gene length, protein length | 282 bp, 94 aa |
| Immediate neighbours | yabC, metS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU00370
Phenotypes of a mutant
No swarming motility on B medium. PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
Genes/ operons controlled by AbrB
- Repressed by AbrB: abrB, aprE, comK, ftsA-ftsZ, kinB, pbpE, sigH, spoVG, spo0E, tycA, sbo-alb, yqxM-sipW-tasA, sdpA operon, sunA, skfA operon, sinI-sinR, sigW, yuaB
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylated on Ser-86 PubMed
- Cofactor(s):
- Localization:
Database entries
- UniProt: P08874
- KEGG entry: [3]
Additional information
Expression and regulation
- Operon: abrB PubMed
- Regulation: expressed at the onset of stationary phase PubMed
- Additional information:
Biological materials
- Mutant: TT731 (aphA3)
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Stülke lab
- Antibody:
Labs working on this gene/protein
Richard Losick, Harvard Univ., Cambridge, USA homepage
Mark Strauch, Baltimore, USA homepage
Your additional remarks
References
Reviews
Original Publications
Other publications: PubMed
