OppF

• Description: oligopeptide ABC transporter (ATP-binding protein)
  
  

Gene name	oppF
Synonyms	spo0KE
Essential	no
Product	oligopeptide ABC transporter (ATP-binding protein)
Function	initiation of sporulation, competence development
Interactions involving this protein in SubtInteract: OppF
Metabolic function and regulation of this protein in SubtiPathways: Alternative nitrogen sources
MW, pI	34 kDa, 6.95
Gene length, protein length	915 bp, 305 aa
Immediate neighbours	oppD, yjbB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

ABC transporters, utilization of nitrogen sources other than amino acids, genetic competence, phosphorelay, membrane proteins

This gene is a member of the following regulons

ScoC regulon, TnrA regulon

The gene

Basic information

• Locus tag: BSU11470

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • required for the uptake of quorum sensing peptides such as PhrH PubMed

• Protein family: ABC transporter domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • (OppD-OppF)-(OppB-OppC)-OppA PubMed

• Localization: attached to the cell membrane (via OppB-OppC) PubMed

Database entries

• Structure:

• UniProt: P24137

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: oppA-oppB-oppC-oppD-oppF PubMed

• Sigma factor:

• Regulation:
  • expressed in the absence of good nitrogen sources (glutamine or ammonium) (TnrA) PubMed
  • repressed during exponential growth (ScoC) PubMed

• Regulatory mechanism:
  • TnrA: transcription activation PubMed
  • ScoC: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed