Difference between revisions of "GalE"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| − | {{SubtiWiki category|[[utilization of specific carbon sources]]}} | + | {{SubtiWiki category|[[utilization of specific carbon sources]]}}, |
| + | {{SubtiWiki category|[[biofilm formation]]}} | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| Line 46: | Line 47: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | ** smooth colonies on MsGG medium, no [[biofilm formation]] {{PubMed|22113911}} | ||
=== Database entries === | === Database entries === | ||
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=References= | =References= | ||
| − | <pubmed>9555917,,14597172 , </pubmed> | + | <pubmed>9555917,22113911,14597172 , </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:41, 25 November 2011
- Description: UDP glucose 4-epimerase
| Gene name | galE |
| Synonyms | |
| Essential | no |
| Product | UDP glucose 4-epimerase |
| Function | galactose utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 36 kDa, 4.776 |
| Gene length, protein length | 1017 bp, 339 aa |
| Immediate neighbours | yxkC, yxkA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
utilization of specific carbon sources, biofilm formation
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU38860
Phenotypes of a mutant
- smooth colonies on MsGG medium, no biofilm formation PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: UDP-glucose = UDP-galactose (according to Swiss-Prot)
- Protein family: sugar epimerase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: P55180
- KEGG entry: [3]
- E.C. number: 5.1.3.2
Additional information
Expression and regulation
- Operon: galE PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Eric R Pozsgai, Kris M Blair, Daniel B Kearns
Modified mariner transposons for random inducible-expression insertions and transcriptional reporter fusion insertions in Bacillus subtilis.
Appl Environ Microbiol: 2012, 78(3);778-85
[PubMed:22113911]
[WorldCat.org]
[DOI]
(I p)
Blazenka Soldo, Claudio Scotti, Dimitri Karamata, Vladimir Lazarevic
The Bacillus subtilis Gne (GneA, GalE) protein can catalyse UDP-glucose as well as UDP-N-acetylglucosamine 4-epimerisation.
Gene: 2003, 319;65-9
[PubMed:14597172]
[WorldCat.org]
[DOI]
(P p)
O Krispin, R Allmansberger
The Bacillus subtilis galE gene is essential in the presence of glucose and galactose.
J Bacteriol: 1998, 180(8);2265-70
[PubMed:9555917]
[WorldCat.org]
[DOI]
(P p)
