Difference between revisions of "MlpA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || control of proteolyticc activity
 
|style="background:#ABCDEF;" align="center"|'''Function''' || control of proteolyticc activity
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU16710 mlpA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16710 mlpA]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 5.275   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 5.275   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylxY]]'', ''[[ymxH]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylxY]]'', ''[[ymxH]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13544&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU16710 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU16710 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU16710 Advanced_DNA]
 
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Revision as of 12:52, 13 May 2013

  • Description: mitochondrial processing peptidase-like, involved in regulation of protease gene expression

Gene name mlpA
Synonyms ymxG
Essential no
Product specific processing protease
Function control of proteolyticc activity
Gene expression levels in SubtiExpress: mlpA
MW, pI 45 kDa, 5.275
Gene length, protein length 1227 bp, 409 aa
Immediate neighbours ylxY, ymxH
Sequences Protein DNA Advanced_DNA
Genetic context
MlpA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MlpA expression.png
























Categories containing this gene/protein

proteolysis

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU16710

Phenotypes of a mutant

fivefold increased levels of proteolytic activity in their growth medium PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase M16 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: deletion mutant, available in van Dijl lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Jan Maarten van Dijl, Groningen, Netherlands

Your additional remarks

References