Difference between revisions of "LipM"

From SubtiWiki
Jump to: navigation, search
Line 14: Line 14:
 
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of lipoic acid
 
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of lipoic acid
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU24530 lipM]
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU24530 lipM]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 32 kDa, 5.934   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 32 kDa, 5.934   
Line 22: Line 22:
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mntR]]'', ''[[yqhL]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mntR]]'', ''[[yqhL]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14384&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU24530 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU24530 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU24530 Advanced_DNA]
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yqhM_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yqhM_context.gif]]

Revision as of 13:16, 13 May 2013

  • Description: octanoyltransferase

Gene name lipM
Synonyms yqhM
Essential no
Product octanoyltransferase
Function biosynthesis of lipoic acid
Gene expression levels in SubtiExpress: lipM
MW, pI 32 kDa, 5.934
Gene length, protein length 834 bp, 278 aa
Immediate neighbours mntR, yqhL
Sequences Protein DNA Advanced_DNA
Genetic context
YqhM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LipM expression.png
























Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU24530

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • transfers the octanoyl moiety from octanoyl-acyl carrier protein to the lipoyl domains of the 2-oxoacid dehydrogenases via a thioester-linked octanoyl-LipM intermediate PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation: induced by valine PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References