Difference between revisions of "CotX"
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| − | ** spore | + | ** spore crust {{PubMed|23202530}} |
=== Database entries === | === Database entries === | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotX_1250656_1251174_-1 cotX] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotX_1250656_1251174_-1 cotX] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' before ''[[cotV]]'': [[SigK]] {{PubMed|15699190,7519271}} | + | * '''[[Sigma factor]]:''' before ''[[cotV]]'': [[SigK]] {{PubMed|15699190,7519271}} |
before ''[[cotX]]'': [[SigK]] [http://www.ncbi.nlm.nih.gov/pubmed/7519271 PubMed] | before ''[[cotX]]'': [[SigK]] [http://www.ncbi.nlm.nih.gov/pubmed/7519271 PubMed] | ||
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=References= | =References= | ||
| − | + | == Reviews == | |
| + | <pubmed>23202530</pubmed> | ||
| + | == Original publications == | ||
<pubmed>7519271,10788508, 20451384,12107147, 21665972 21821766</pubmed> | <pubmed>7519271,10788508, 20451384,12107147, 21665972 21821766</pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:26, 4 January 2014
- Description: spore coat protein (insoluble fraction), necessary for the assembly of the spore crust, the outermost layer of the spore coat
| Gene name | cotX |
| Synonyms | |
| Essential | no |
| Product | spore coat protein (insoluble fraction) |
| Function | spore coat assembly |
| Gene expression levels in SubtiExpress: cotX | |
| MW, pI | 18 kDa, 4.228 |
| Gene length, protein length | 516 bp, 172 aa |
| Immediate neighbours | cotY, cotW |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU11760
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
- A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Localization:
- spore crust PubMed
Database entries
- Structure:
- UniProt: Q08313
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
cotX PubMed
- Sigma factor: before cotV: SigK PubMed
- Regulation: repressed by casamino acids PubMed
- Regulatory mechanism: upstream of cotX: SpoIIID: repression PubMed, upstream of both promoters: GerE: transcription activation PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Peter T McKenney, Adam Driks, Patrick Eichenberger
The Bacillus subtilis endospore: assembly and functions of the multilayered coat.
Nat Rev Microbiol: 2013, 11(1);33-44
[PubMed:23202530]
[WorldCat.org]
[DOI]
(I p)
Original publications
