MrpB

• Description: Na+/H+ antiporter subunit, multiple resistance and pH homeostasis
  
  

Gene name	mrpB
Synonyms	yufU
Essential	yes PubMed
Product	Na+/H+ antiporter subunit
Function	sodium export
Gene expression levels in SubtiExpress: mrpB
Interactions involving this protein in SubtInteract: MprB
MW, pI	15 kDa, 4.912
Gene length, protein length	429 bp, 143 aa
Immediate neighbours	mrpA, mrpC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), essential genes, membrane proteins

The gene

Basic information

• Locus tag: BSU31610

Phenotypes of a mutant

essential PubMed

Database entries

• BsubCyc: BSU31610

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • MrpA-MrpB-MrpC-MrpD-MrpE-MrpF-MrpG (complex)

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU31610

• Structure:

• UniProt: O05259

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: mrpA-mrpB-mrpC-mrpD-mrpE-mrpF-mrpG PubMed

• Expression browser: mrpB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • SM-GN9 (mrpB-spc), available in Anne Galinier's and Boris Görke's labs

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: