MprF

• Description: synthesis of lysylphosphatidylglycerol (L-PG), lysinylation of phosphatidylglycerol provides some resistance against positively charged antimicrobial peptides
  
  

Gene name	mprF
Synonyms	yfiW, yfiX
Essential	no
Product	lysyl-phosphatidylglycerol synthase
Function	lysyl-phosphatidylglycerol lipid biosynthesis
Gene expression levels in SubtiExpress: mprF
Metabolic function and regulation of this protein in SubtiPathways: mprF
MW, pI	96 kDa, 9.498
Gene length, protein length	2568 bp, 856 aa
Immediate neighbours	yfiV, yfiY
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of lipids, membrane proteins

The gene

Basic information

• Locus tag: BSU08425

Database entries

• BsubCyc: BSU08425

• DBTBS entry: [1]

• SubtiList entry: old_YfiWold_YfiX

Additional information

Gene was re-assembled due to sequencing error in original sequence (it encompasses the genes annotated as yfiX and yfiW in SubtiList) PubMed

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane at the septum PubMed

Database entries

• BsubCyc: BSU08425

• Structure:

• UniProt: C0H3X7

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: mprF (according to DBTBS)

• Expression browser: mprF PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: