Difference between revisions of "CsfB"
| Line 44: | Line 44: | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | {{SubtiWiki regulon|[[SigF regulon]]}} | + | {{SubtiWiki regulon|[[SigF regulon]]}}, |
| + | {{SubtiWiki regulon|[[SigK regulon]]}} | ||
=The gene= | =The gene= | ||
| Line 53: | Line 54: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * premature activation of [[SigG]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17921305 PubMed] | ||
| − | |||
=== Database entries === | === Database entries === | ||
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00240&redirect=T BSU00240] | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00240&redirect=T BSU00240] | ||
| Line 87: | Line 88: | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| − | ** [[CsfB]]-[[SigG]] [ | + | ** [[CsfB]]-[[SigG]] to inhibit [[SigG]] activity {{PubMed|25835496,19497328}} |
| + | ** [[CsfB]]-[[SigE]] to inhibit [[SigE]] activity {{PubMed|25835496}} | ||
| − | * '''[[Localization]]:''' forespore | + | * '''[[Localization]]:''' forespore and mother cell {{PubMed|25835496}} |
=== Database entries === | === Database entries === | ||
| Line 106: | Line 108: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''csfB'' | + | * '''Operon:''' ''csfB'' {{PubMed|22383849}} |
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=csfB_35531_35725_1 csfB] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=csfB_35531_35725_1 csfB] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigF]] [ | + | * '''Sigma factor:''' |
| + | ** [[SigF]] {{PubMed|16497325}}, [[SigK]] {{PubMed|25835496}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | + | ** expressed early during [[sporulation]] in the forespore ([[SigF]]) {{PubMed|16497325}} | |
| + | ** expressed after completion of forespore engulfment in the mother cell ([[SigK]]) {{PubMed|25835496}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| Line 137: | Line 141: | ||
=References= | =References= | ||
| − | <pubmed>7592342,19497328,8759874,18208527 16497325 17921305, 20802044,21935351 25835496</pubmed> | + | <pubmed>7592342,19497328,8759874,18208527 16497325 17921305, 20802044,21935351 25835496 22383849</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 13:28, 6 April 2015
| Gene name | csfB |
| Synonyms | gin, yaaM |
| Essential | no |
| Product | inhibitor of SigG and SigE |
| Function | control of SigG and SigE activity |
| Gene expression levels in SubtiExpress: csfB | |
| Interactions involving this protein in SubtInteract: CsfB | |
| MW, pI | 7 kDa, 7.671 |
| Gene length, protein length | 192 bp, 64 aa |
| Immediate neighbours | rrnA-5S, xpaC |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
sigma factors and their control, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00240
Phenotypes of a mutant
Database entries
- BsubCyc: BSU00240
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: forespore and mother cell PubMed
Database entries
- BsubCyc: BSU00240
- Structure:
- UniProt: P37534
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: csfB PubMed
- Regulation:
- expressed early during sporulation in the forespore (SigF) PubMed
- expressed after completion of forespore engulfment in the mother cell (SigK) PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
