Difference between revisions of "YclM"

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(This gene is a member of the following regulons)
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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
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* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
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* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:''' inhibited by the simultaneous presence of threonine and lysine {{PubMed|11471740}}  
 
* '''Effectors of protein activity:''' inhibited by the simultaneous presence of threonine and lysine {{PubMed|11471740}}  
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yclM_430623_431987_-1 yclM] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yclM_430623_431987_-1 yclM] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
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* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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** [[CodY]]: transcription repression {{PubMed|23569278}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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<pubmed>19946135 ,, </pubmed>
 
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==Original publications==
 
==Original publications==
<pubmed>11471740,,2152900, </pubmed>
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[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 15:08, 19 May 2015

  • Description: aspartokinase III

Gene name yclM
Synonyms
Essential no
Product aspartokinase III
Function unknown
Gene expression levels in SubtiExpress: yclM
Metabolic function and regulation of this protein in SubtiPathways:
yclM
MW, pI 49 kDa, 4.783
Gene length, protein length 1362 bp, 454 aa
Immediate neighbours yczN, yclN
Sequences Protein DNA DNA_with_flanks
Genetic context
YclM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YclM expression.png















Categories containing this gene/protein

biosynthesis/ acquisition of amino acids

This gene is a member of the following regulons

CodY regulon

The gene

Basic information

  • Locus tag: BSU03790

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + L-aspartate = ADP + 4-phospho-L-aspartate (according to Swiss-Prot)
  • Protein family: aspartokinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity: inhibited by the simultaneous presence of threonine and lysine PubMed

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 78 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications