Difference between revisions of "YabM"
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| − | * '''Description:''' | + | * '''Description:''' may function in a previously observed alternate pathway for peptidoglycan strand synthesis <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Product''' || unknown | |style="background:#ABCDEF;" align="center"| '''Product''' || unknown | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || alternate pathway for peptidoglycan strand synthesis |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 57 kDa, 9.623 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 57 kDa, 9.623 | ||
| Line 38: | Line 38: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | |||
| + | Mutants lacking YabM exhibit sensitivity to moenomycin, an antibiotic that blocks peptidoglycan polymerization by class A penicillin-binding proteins. {{PubMed| 19648239}} | ||
=== Database entries === | === Database entries === | ||
| Line 56: | Line 58: | ||
* '''Protein family:''' polysaccharide synthase family (according to Swiss-Prot) | * '''Protein family:''' polysaccharide synthase family (according to Swiss-Prot) | ||
| − | * '''Paralogous protein(s):''' | + | * '''Paralogous protein(s):''' [[SpoVB]], [[YkvU]], [[YtgP]] |
=== Extended information on the protein === | === Extended information on the protein === | ||
| Line 117: | Line 119: | ||
=References= | =References= | ||
| − | <pubmed>11283287 </pubmed> | + | <pubmed>11283287 19648239 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:44, 4 August 2009
- Description: may function in a previously observed alternate pathway for peptidoglycan strand synthesis
| Gene name | yabM |
| Synonyms | |
| Essential | no |
| Product | unknown |
| Function | alternate pathway for peptidoglycan strand synthesis |
| MW, pI | 57 kDa, 9.623 |
| Gene length, protein length | 1596 bp, 532 aa |
| Immediate neighbours | spoVT, yabN |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU00570
Phenotypes of a mutant
Mutants lacking YabM exhibit sensitivity to moenomycin, an antibiotic that blocks peptidoglycan polymerization by class A penicillin-binding proteins. 19648239 PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: polysaccharide synthase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P37555
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
