Difference between revisions of "SigD"
| Line 86: | Line 86: | ||
* '''E.C. number:''' | * '''E.C. number:''' | ||
| − | |||
=== Additional information=== | === Additional information=== | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ** ''[[flgB]]-[[flgC]]-[[fliE]]-[[fliF]]-[[fliG]]-[[fliH]]-[[fliI]]-[[fliJ]]-[[ylxF]]-[[fliK]]-[[ylxG]]-[[flgE]]-[[fliL]]-[[fliM]]-[[fliY]]-[[cheY]]-[[fliZ]]-[[fliP]]-[[fliQ]]-[[fliR]]-[[flhB]]-[[flhA]]-[[flhF]]-[[ylxH]]-[[cheB]]-[[cheA]]-[[cheW]]-[[cheC]]-[[cheD]]-[[sigD]]-[[ylxL]]'' {{PubMed|9657996,8157612,15175317}} |
| + | ** ''[[sigD]]-[[ylxL]]'' {{PubMed|9335309}} | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| + | ** ''[[flgB]]'': [[SigA]] {{PubMed|9657996}}, [[SigD]] {{PubMed|9657996}} | ||
| + | ** ''[[sigD]]'': [[SigA]] {{PubMed|9335309}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** repressed under conditions that trigger sporulation ([[Spo0A]]) | + | ** ''[[flgB]]'' promoter: repressed under conditions that trigger sporulation ([[Spo0A]]) {{PubMed|14651647}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[Spo0A]]: transcription repression | + | ** [[Spo0A]]: transcription repression {{PubMed|14651647}} |
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 123: | Line 125: | ||
=References= | =References= | ||
| − | <pubmed>8955328,7708689,15033535,9648743,8169223,9096206,15175317,2498284,16357223,3127378,9144176,18820022,2111808,7602586,2832368,8195064,11987133,,14651647, </pubmed> | + | <pubmed>8955328,7708689,15033535,9648743,8169223,9096206,15175317,2498284,16357223,3127378,9144176,18820022,2111808,7602586,2832368,8195064,11987133,,14651647, 9335309 9657996,8157612,15175317 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:47, 11 October 2009
- Description: RNA polymerase sigma factor SigD
| Gene name | sigD |
| Synonyms | flaB |
| Essential | no |
| Product | RNA polymerase sigma factor SigD |
| Function | regulation of flagella, motility, chemotaxis and autolysis |
| MW, pI | 29 kDa, 5.167 |
| Gene length, protein length | 762 bp, 254 aa |
| Immediate neighbours | cheD, swrB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU16470
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: sigma-70 factor family (according to Swiss-Prot)
- Paralogous protein(s):
Genes/ operons controlled by SigD
dltA-dltB-dltC-dltD-dltE, cheV, degR, epr, hag, lytA-lytB-lytC, lytD, lytF, tlpA-mcpA, mcpB, mcpC, motA-motB, nfrA-ywcH
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P10726
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: ** flgB-flgC-fliE-fliF-fliG-fliH-fliI-fliJ-ylxF-fliK-ylxG-flgE-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-ylxH-cheB-cheA-cheW-cheC-cheD-sigD-ylxL PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Stülke lab
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
