Difference between revisions of "FadN"
| Line 87: | Line 87: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | + | * '''Operon:''' | |
| − | * '''Operon:''' | + | ** ''[[fadM]]-[[fadN]]-[[fadA]]-[[fadE]]'' {{PubMed|17189250}} |
| + | ** ''[[fadN]]-[[fadA]]-[[fadE]]'' {{PubMed|17189250}} | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| + | ** ''[[fadN]]'': [[SigA]] {{PubMed|17189250}} | ||
| − | * '''Regulation:''' | + | * '''Regulation:''' |
| − | ** | + | ** ''[[fadN]]'': induced by long-chain fatty acids ([[FadR]]) {{PubMed|17189250}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[FadR]]: transcription repression [ | + | ** [[FadR]]: transcription repression {{PubMed|17189250}} |
| + | ** [[SdpR]]: transcription activation {{PubMed|12817086}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 120: | Line 123: | ||
=References= | =References= | ||
| − | <pubmed> | + | <pubmed>12817086,12850135 17189250, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:28, 28 December 2009
- Description: 3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA)
| Gene name | fadN |
| Synonyms | yusL |
| Essential | no |
| Product | 3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA) |
| Function | fatty acid degradation |
| MW, pI | 89 kDa, 6.53 |
| Gene length, protein length | 2445 bp, 815 aa |
| Immediate neighbours | fadA, fadM |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU32840
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH (according to Swiss-Prot)
- Protein family: 3-hydroxyacyl-CoA dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O32178
- KEGG entry: [3]
- E.C. number: 1.1.1.35
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
