Difference between revisions of "MreBH"

From SubtiWiki
Jump to: navigation, search
Line 1: Line 1:
* '''Description:''' cell-shape determining protein<br/><br/>
+
* '''Description:''' cell-shape determining protein, forms filaments<br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
Line 53: Line 53:
  
 
* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
 +
** forms ring-shaped filaments in a heterologous system {{PubMed|21091501}}
  
 
* '''Protein family:''' ftsA/mreB family (according to Swiss-Prot)
 
* '''Protein family:''' ftsA/mreB family (according to Swiss-Prot)
Line 124: Line 125:
 
<pubmed> 17064365,  20566861  </pubmed>
 
<pubmed> 17064365,  20566861  </pubmed>
 
==Other original publications==
 
==Other original publications==
<pubmed>16950129,19643765 ,16950129 18156261, 19659933 </pubmed>
+
<pubmed>16950129,19643765 ,16950129 18156261, 19659933 21091501</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:33, 28 November 2010

  • Description: cell-shape determining protein, forms filaments

Gene name mreBH
Synonyms
Essential no
Product cell-shape determining protein
Function cell-shape determation
MW, pI 35 kDa, 5.239
Gene length, protein length 1005 bp, 335 aa
Immediate neighbours ykpC, abh
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MreBH context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU14470

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • forms ring-shaped filaments in a heterologous system PubMed
  • Protein family: ftsA/mreB family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • forms helical structures close to the inner surface of the cytoplasmic membrane PubMed
    • formation of helical clusters depends on the proton motive force PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Peter Graumann, Freiburg University, Germany homepage

Your additional remarks

References

Localization

Henrik Strahl, Leendert W Hamoen
Membrane potential is important for bacterial cell division.
Proc Natl Acad Sci U S A: 2010, 107(27);12281-6
[PubMed:20566861] [WorldCat.org] [DOI] (I p)

Hervé Joël Defeu Soufo, Peter L Graumann
Dynamic localization and interaction with other Bacillus subtilis actin-like proteins are important for the function of MreB.
Mol Microbiol: 2006, 62(5);1340-56
[PubMed:17064365] [WorldCat.org] [DOI] (P p)

Other original publications