Difference between revisions of "YodB"
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[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 11:19, 26 December 2011
Gene name | yodB |
Synonyms | |
Essential | no |
Product | MarR/DUF24-family transcription repressor |
Function | regulation of quinone and diamide detoxification |
MW, pI | 12 kDa, 4.737 |
Gene length, protein length | 336 bp, 112 aa |
Immediate neighbours | yodA, yodC |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
transcription factors and their control, resistance against oxidative and electrophile stress
This gene is a member of the following regulons
The YodB regulon:
The gene
Basic information
- Locus tag: BSU19540
Phenotypes of a mutant
increased resistance to catechol, quinones and diamide PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: MarR/DUF24-family
- Paralogous protein(s): CatR
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: redox-controlled by intersubunit disulfide formation of Cys6 and Cys101' in response to quinones and diamide
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34844
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- subject to autorepression PubMed
- Regulatory mechanism:
- YodB: transcription repression PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Haike Antelmann,University of Greifswald, Germany
Your additional remarks
References
Reviews
Haike Antelmann, John D Helmann
Thiol-based redox switches and gene regulation.
Antioxid Redox Signal: 2011, 14(6);1049-63
[PubMed:20626317]
[WorldCat.org]
[DOI]
(I p)
Original Publications