SpoIVA

• Description: spore coat morphogenetic protein, anchors the spore coat to the spore surface via SpoVM
  
  

Gene name	spoIVA
Synonyms	spoVP
Essential	no
Product	basement layer protein for spore coat assembly
Function	spore cortex formation and coat assembly
Interactions involving this protein in SubtInteract: SpoIVA
MW, pI	55 kDa, 4.546
Gene length, protein length	1476 bp, 492 aa
Immediate neighbours	hbs, yphF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU22800

Phenotypes of a mutant

• the spore coat does not localize to the spore surface but self-assembles into aggregates in the mother cell cytoplasm PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • SpoIVA-SpoVID PubMed
  • SpoIVA-SafA PubMed
  • SpoIVA-SpoVM-SpoVID PubMed

• Localization:
  • spore coat PubMed

Database entries

• Structure:

• UniProt: P35149

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoIVA PubMed

• Expression browser: spoIVA PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed early during sporulation in the mother cell (SigE, SpoIIID) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed