Difference between revisions of "YloS"

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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
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* '''[[SubtInteract|Interactions]]:'''
  
* '''Localization:'''
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* '''[[Localization]]:'''
  
 
=== Database entries ===
 
=== Database entries ===
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=thiN_1654730_1655374_1 yloS] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=thiN_1654730_1655374_1 yloS] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
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* '''Regulation:'''  
 
* '''Regulation:'''  

Revision as of 20:14, 28 November 2012

  • Description: thiamine pyrophosphokinase

Gene name yloS
Synonyms thiN
Essential no
Product thiamine pyrophosphokinase
Function thiamine salvage
Gene expression levels in SubtiExpress: yloS
Metabolic function and regulation of this protein in SubtiPathways:
Thiamin
MW, pI 23 kDa, 5.216
Gene length, protein length 642 bp, 214 aa
Immediate neighbours rpe, spoVM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YloS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YloS expression.png















Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15800

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + thiamine = AMP + thiamine diphosphate (according to Swiss-Prot)
  • Protein family: thiamine pyrophosphokinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Christopher T Jurgenson, Tadhg P Begley, Steven E Ealick
The structural and biochemical foundations of thiamin biosynthesis.
Annu Rev Biochem: 2009, 78;569-603
[PubMed:19348578] [WorldCat.org] [DOI] (I p)

Original publications