Difference between revisions of "BcrC"
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|style="background:#ABCDEF;" align="center"|'''Function''' || [[cell wall synthesis]], resistance to bacitracin and oxidative stress | |style="background:#ABCDEF;" align="center"|'''Function''' || [[cell wall synthesis]], resistance to bacitracin and oxidative stress | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36530 bcrC] |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 21 kDa, 9.455 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 21 kDa, 9.455 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nrgB]]'', ''[[ywnJ]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nrgB]]'', ''[[ywnJ]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU36530 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU36530 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU36530 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:ywoA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ywoA_context.gif]] | ||
Revision as of 14:03, 13 May 2013
- Description: undecaprenyl pyrophosphate phosphatase, produces the carrier lipid for cell wall synthesis, bacitracin resistance
| Gene name | bcrC |
| Synonyms | ywoA |
| Essential | no |
| Product | undecaprenyl pyrophosphate phosphatase |
| Function | cell wall synthesis, resistance to bacitracin and oxidative stress |
| Gene expression levels in SubtiExpress: bcrC | |
| MW, pI | 21 kDa, 9.455 |
| Gene length, protein length | 579 bp, 193 aa |
| Immediate neighbours | nrgB, ywnJ |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
cell wall synthesis, cell envelope stress proteins (controlled by SigM, V, W, X, Y), heat shock proteins, resistance against toxins/ antibiotics, membrane proteins
This gene is a member of the following regulons
SigI regulon, SigM regulon, SigW regulon, SigX regulon
The gene
Basic information
- Locus tag: BSU36530
Phenotypes of a mutant
- increased susceptibility to rare earth elements PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- undecaprenyl pyrophosphate --> undecaprenyl phosphate
- Protein family: bcrC/ybjG/ywoA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P94571
- KEGG entry: [2]
- E.C. number:
Additional information
- there is a second undecaprenyl pyrophosphate phosphatase in B. subtilis, YubB. However, YubB seems to play only a minor role. PubMed
Expression and regulation
- Operon: bcrC
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
