Difference between revisions of "BshB2"

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* '''Description:''' N-acetylglucosamin-malate deacetylase, involved in bacillithiol synthesis  <br/><br/>
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* '''Description:''' N-acetylglucosamine-malate deacetylase, minor enzyme involved in bacillithiol synthesis, may act as amidase for the processing of BSH conjugates <br/><br/>
  
 
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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
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{{SubtiWiki regulon|[[Spx regulon]]}}
  
  
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''[[yoyC]]-[[yojF]]-[[bshB2]]'' {{PubMed|20308541}}
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* '''Operon:'''
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** ''[[yojE]]-[[yoyC]]-[[yojF]]-[[bshB2]]'' (minor transcript) {{PubMed|23894131}}
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** ''[[yoyC]]-[[yojF]]-[[bshB2]]'' (major transcript) {{PubMed|23894131,20308541}}
  
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yojG_2121641_2122306_-1 bshB2] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yojG_2121641_2122306_-1 bshB2] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
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* '''[[Sigma factor]]:'''  
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** ''[[yojE]]'': [[SigA]] {{PubMed|23894131}}
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** ''[[yoyC]]'': [[SigA]] {{PubMed|23894131}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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** ''[[yoyC]]'': induced by diamide stess (thiol depletion) ([[Spx]]) {{PubMed|23894131}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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** [[Spx]]: transcription activation {{PubMed|23894131}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
<pubmed> 20308541 19578333 </pubmed>
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<pubmed> 20308541 19578333 23894131</pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 12:23, 1 August 2013

  • Description: N-acetylglucosamine-malate deacetylase, minor enzyme involved in bacillithiol synthesis, may act as amidase for the processing of BSH conjugates

Gene name bshB2
Synonyms yojG
Essential no
Product N-acetylglucosamin-malate deacetylase
Function biosynthesis of bacillithiol
Gene expression levels in SubtiExpress: bshB2
MW, pI 16 kDa, 4.511
Gene length, protein length 426 bp, 142 aa
Immediate neighbours rsbRC, yojF
Sequences Protein DNA DNA_with_flanks
Genetic context
YojG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
BshB2 expression.png















Categories containing this gene/protein

miscellaneous metabolic pathways, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

Spx regulon


The gene

Basic information

  • Locus tag: BSU19460

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): BshB1

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References