Difference between revisions of "BshB2"
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− | * '''Description:''' N- | + | * '''Description:''' N-acetylglucosamine-malate deacetylase, minor enzyme involved in bacillithiol synthesis, may act as amidase for the processing of BSH conjugates <br/><br/> |
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
+ | {{SubtiWiki regulon|[[Spx regulon]]}} | ||
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=Expression and regulation= | =Expression and regulation= | ||
− | * '''Operon:''' ''[[yoyC]]-[[yojF]]-[[bshB2]]'' | + | * '''Operon:''' |
+ | ** ''[[yojE]]-[[yoyC]]-[[yojF]]-[[bshB2]]'' (minor transcript) {{PubMed|23894131}} | ||
+ | ** ''[[yoyC]]-[[yojF]]-[[bshB2]]'' (major transcript) {{PubMed|23894131,20308541}} | ||
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yojG_2121641_2122306_-1 bshB2] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yojG_2121641_2122306_-1 bshB2] {{PubMed|22383849}} | ||
− | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
+ | ** ''[[yojE]]'': [[SigA]] {{PubMed|23894131}} | ||
+ | ** ''[[yoyC]]'': [[SigA]] {{PubMed|23894131}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
+ | ** ''[[yoyC]]'': induced by diamide stess (thiol depletion) ([[Spx]]) {{PubMed|23894131}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
+ | ** [[Spx]]: transcription activation {{PubMed|23894131}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
− | <pubmed> 20308541 19578333 </pubmed> | + | <pubmed> 20308541 19578333 23894131</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 12:23, 1 August 2013
- Description: N-acetylglucosamine-malate deacetylase, minor enzyme involved in bacillithiol synthesis, may act as amidase for the processing of BSH conjugates
Gene name | bshB2 |
Synonyms | yojG |
Essential | no |
Product | N-acetylglucosamin-malate deacetylase |
Function | biosynthesis of bacillithiol |
Gene expression levels in SubtiExpress: bshB2 | |
MW, pI | 16 kDa, 4.511 |
Gene length, protein length | 426 bp, 142 aa |
Immediate neighbours | rsbRC, yojF |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, resistance against oxidative and electrophile stress
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU19460
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): BshB1
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31857
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant: bshB2 null mutant and bshB1 / bshB2 double null mutant available in John Helmann lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References