Difference between revisions of "BslA"
(→Reviews) |
(→Expression and regulation) |
||
Line 114: | Line 114: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
− | |||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
+ | ** [[AbrB]]: transcription repression {{PubMed|18978066}} | ||
+ | ** [[LutR]]: transcription activation {{PubMed|24196425}} | ||
+ | ** expression is down-regulated in a ''[[rok]]'' mutant (indirect effect) {{PubMed|21097620}} | ||
** [[DegU]]-P: transcription activation {{PubMed|18978066}}, this might be indirect {{PubMed|21742882}} | ** [[DegU]]-P: transcription activation {{PubMed|18978066}}, this might be indirect {{PubMed|21742882}} | ||
− | + | ||
* '''Additional information:''' | * '''Additional information:''' |
Revision as of 15:36, 8 November 2013
- Description: bacterial hydrophobin, forms water-repellent surface layer of the biofilm, inhibitor of KinA autophosphorylation, and subsequently of entry into sporulation
Gene name | bslA |
Synonyms | yuaB, sivB |
Essential | no |
Product | biofilm surface layer, inhibitor of KinA autophosphorylation |
Function | biofilm formation, control of entry into sporulation via the phosphorelay |
Gene expression levels in SubtiExpress: bslA | |
MW, pI | 19 kDa, 9.987 |
Gene length, protein length | 543 bp, 181 aa |
Immediate neighbours | gbsR, ktrA |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
biofilm formation, phosphorelay
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU31080
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Protein family:
- Paralogous protein(s): SivA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: P71014
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- Physpank-bslA based on vector pDR111: pDRyuaB2 PubMed
- lacZ fusion:
- pNW500 PbslA-lacZ fusion in pDG1663 PubMed
- GFP fusion:
- PbslA-gfp fusion in pSG1151 vector: pSGyuaB PubMed
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Ursula Hofer
Bacterial physiology: a raincoat for Bacillus subtilis.
Nat Rev Microbiol: 2013, 11(10);660-1
[PubMed:23979433]
[WorldCat.org]
[DOI]
(I p)
Akos T Kovács, Jordi van Gestel, Oscar P Kuipers
The protective layer of biofilm: a repellent function for a new class of amphiphilic proteins.
Mol Microbiol: 2012, 85(1);8-11
[PubMed:22607588]
[WorldCat.org]
[DOI]
(I p)
Original publications