Difference between revisions of "YidC2"

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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
  
* '''Protein family:'''
+
* '''Protein family:''' YidC/Oxa1/Alb3 family {{PubMed|20800571,21194367,15802250}}
  
 
* '''Paralogous protein(s):''' [[SpoIIIJ]], one of the two proteins has to be present for viability [http://www.ncbi.nlm.nih.gov/sites/entrez/17114254 PubMed]
 
* '''Paralogous protein(s):''' [[SpoIIIJ]], one of the two proteins has to be present for viability [http://www.ncbi.nlm.nih.gov/sites/entrez/17114254 PubMed]
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=References=
 
=References=
 
==Reviews==
 
==Reviews==
<pubmed>22688815 </pubmed>
+
<pubmed>22688815 20800571,21194367,15802250</pubmed>
 
== Original publications ==
 
== Original publications ==
 
<pubmed>17114254, 15995216, 11889108, 12586834 19717609 19779460 21204254 22383849 22864117 24443530 </pubmed>
 
<pubmed>17114254, 15995216, 11889108, 12586834 19717609 19779460 21204254 22383849 22864117 24443530 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 10:28, 21 January 2014

  • Description: Sec-independent membrane protein translocase, required for competence development

Gene name yidC2
Synonyms yqjG, oxaAB
Essential no
Product Sec-independent membrane protein translocase
Function membrane insertion of proteins and protein secretion
MW, pI 30 kDa, 9.903
Gene length, protein length 825 bp, 275 aa
Immediate neighbours mifM, yqjF
Sequences Protein DNA DNA_with_flanks
Genetic context
YqjG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YqjG expression.png















Categories containing this gene/protein

protein secretion, membrane proteins

This gene is a member of the following regulons

MifM regulon

The gene

Basic information

  • Locus tag: BSU23890

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: YidC/Oxa1/Alb3 family PubMed
  • Paralogous protein(s): SpoIIIJ, one of the two proteins has to be present for viability PubMed

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
    • MifM: "attenuation mechanism", an mRNA hairpin of the yqjG transcript unfold upon translation arrest of MifM at decreased SpoIIIJ levels PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Ross E Dalbey, Peng Wang, Jan Maarten van Dijl
Membrane proteases in the bacterial protein secretion and quality control pathway.
Microbiol Mol Biol Rev: 2012, 76(2);311-30
[PubMed:22688815] [WorldCat.org] [DOI] (I p)

Soledad Funes, Frank Kauff, Eli O van der Sluis, Martin Ott, Johannes M Herrmann
Evolution of YidC/Oxa1/Alb3 insertases: three independent gene duplications followed by functional specialization in bacteria, mitochondria and chloroplasts.
Biol Chem: 2011, 392(1-2);13-9
[PubMed:21194367] [WorldCat.org] [DOI] (I p)

Peng Wang, Ross E Dalbey
Inserting membrane proteins: the YidC/Oxa1/Alb3 machinery in bacteria, mitochondria, and chloroplasts.
Biochim Biophys Acta: 2011, 1808(3);866-75
[PubMed:20800571] [WorldCat.org] [DOI] (P p)

Martin van der Laan, Nico P Nouwen, Arnold J M Driessen
YidC--an evolutionary conserved device for the assembly of energy-transducing membrane protein complexes.
Curr Opin Microbiol: 2005, 8(2);182-7
[PubMed:15802250] [WorldCat.org] [DOI] (P p)

Original publications