YodB

• Description: repressor (MarR-type) of spx, yodC and azoR1 expression, induction in the presence of quinones due to the formation of YodB-Cys6-S-adducts
  
  

Gene name	yodB
Synonyms
Essential	no
Product	transcriptional repressor (MarR-type)
Function	regulation of quinone detoxification
MW, pI	12 kDa, 4.737
Gene length, protein length	336 bp, 112 aa
Immediate neighbours	yodA, yodC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transcription factors and their control, resistance against oxidative and electrophile stress

The gene

Basic information

• Locus tag: BSU19540

Phenotypes of a mutant

increased resistance to catechol and quinones PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: SunT subfamily (according to Swiss-Prot)

• Paralogous protein(s): CatR

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34844

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Haike Antelmann, John D Helmann
Thiol-based redox switches and gene regulation.
Antioxid Redox Signal: 2011, 14(6);1049-63
[PubMed:20626317] [WorldCat.org] [DOI] (I p)