YofA

• Description: transcriptional activator of ftsW at the onset of stationary phase
  
  

Gene name	yofA
Synonyms
Essential	no
Product	transcriptional activator (LysR family)
Function	control of ftsW expression
MW, pI	31 kDa, 6.164
Gene length, protein length	855 bp, 285 aa
Immediate neighbours	ggt, yogA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transcription factors and their control

The YofA regulon:

• ftsW

The gene

Basic information

• Locus tag: BSU18420

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: LysR family

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: secreted (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O34685

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yofA (according to DBTBS)

• Sigma factor:

• Regulation:
  • maximally expressed at the onset of stationary phase PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Zuolei Lu, Michio Takeuchi, Tsutomu Sato
The LysR-type transcriptional regulator YofA controls cell division through the regulation of expression of ftsW in Bacillus subtilis.
J Bacteriol: 2007, 189(15);5642-51
[PubMed:17526699] [WorldCat.org] [DOI] (P p)