SkfF

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Gene name skfF
Synonyms ybdB
Essential no
Product ABC transporter (permease)
Function export of the spore killing factor SkfA
Gene expression levels in SubtiExpress: skfF
Interactions involving this protein in SubtInteract: SkfF
MW, pI 51 kDa, 9.222
Gene length, protein length 1344 bp, 448 aa
Immediate neighbours skfE, skfG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YbdB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SkfF expression.png
























Categories containing this gene/protein

ABC transporters, toxins, antitoxins and immunity against toxins, membrane proteins

This gene is a member of the following regulons

AbrB regulon, PhoP regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU01960

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
    • repressed during logrithmic growth (AbrB) PubMed
    • induced by phosphate starvation (PhoP) PubMed
  • Additional information: Northern blotting during during phosphate limitation showed an intense 0.25 kb skfA-specific transcript, and a weaker 6.5 kb skfA-skfB-skfC-skfE-skfF-skfG-skfH transcript. PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

José Eduardo González-Pastor
Cannibalism: a social behavior in sporulating Bacillus subtilis.
FEMS Microbiol Rev: 2011, 35(3);415-24
[PubMed:20955377] [WorldCat.org] [DOI] (I p)

Original Publications