YxeB

• Description: hydroxamate siderophore ABC transporter (only ferrioxamine) (binding protein)
  
  

Gene name	yxeB
Synonyms
Essential	no
Product	hydroxamate siderophore ABC transporter (only ferrioxamine) (binding protein)
Function	siderophore uptake
Gene expression levels in SubtiExpress: yxeB
Interactions involving this protein in SubtInteract: YxeB
MW, pI	35 kDa, 5.533
Gene length, protein length	957 bp, 319 aa
Immediate neighbours	yxeC, yxeA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, acquisition of iron, iron metabolism

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

• Locus tag: BSU39610

Phenotypes of a mutant

• no growth with the xenosiderophore ferrioxamine E as single source of iron PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: bacterial solute-binding protein 8 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • FhuC-(FhuB-FhuG)-(FhuD-YxeB) PubMed

• Localization:
  • extracellular (signal peptide) PubMed
  • membrane, lipid modification as retention signal PubMed

Database entries

• Structure:

• UniProt: P54941

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yxeB

• Expression browser: yxeB PubMed

• Sigma factor:

• Regulation:
  • repressed unless the cells enter an iron starvation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: