OppC

• Description: oligopeptide ABC transporter (permease)
  
  

Gene name	oppC
Synonyms	spo0KC
Essential	no
Product	oligopeptide ABC transporter (permease)
Function	initiation of sporulation, competence development
Gene expression levels in SubtiExpress: oppC
Interactions involving this protein in SubtInteract: OppC
Metabolic function and regulation of this protein in SubtiPathways: Alternative nitrogen sources
MW, pI	33 kDa, 10.107
Gene length, protein length	915 bp, 305 aa
Immediate neighbours	oppB, oppD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, utilization of nitrogen sources other than amino acids, genetic competence, phosphorelay, membrane proteins

This gene is a member of the following regulons

ScoC regulon, TnrA regulon

The gene

Basic information

• Locus tag: BSU11450

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • required for the uptake of quorum sensing peptides such as PhrH PubMed

• Protein family: ABC transmembrane type-1 domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • (OppD-OppF)-(OppB-OppC)-OppA PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: P24139

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: oppA-oppB-oppC-oppD-oppF PubMed

• Expression browser: oppC PubMed

• Sigma factor:

• Regulation:
  • expressed in the absence of good nitrogen sources (glutamine or ammonium) (TnrA) PubMed
  • repressed during exponential growth (ScoC) PubMed

• Regulatory mechanism:
  • TnrA: transcription activation PubMed
  • ScoC: transcription repression PubMed

• Additional information:

Biological materials

• Mutant: BP68 (spc) available in Fabian Commichau's lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed