TyrS

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  • Description: tyrosyl-tRNA synthetase (major)

Gene name tyrS
Synonyms
Essential yes PubMed
Product tyrosyl-tRNA synthetase (major)
Function translation
Gene expression levels in SubtiExpress: tyrS
Metabolic function and regulation of this protein in SubtiPathways:
tRNA charging
MW, pI 47 kDa, 5.213
Gene length, protein length 1266 bp, 422 aa
Immediate neighbours rpsD, ytzK
Sequences Protein DNA DNA_with_flanks
Genetic context
TyrS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TyrS expression.png















Categories containing this gene/protein

translation, essential genes

This gene is a member of the following regulons

T-box

The gene

Basic information

  • Locus tag: BSU29670

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
    • 1JH3 (C-terminal domain, Geobacillus stearothermophilus)
    • 3TS1 (complex with tyrosyl adenylate intermediate, Geobacillus stearothermophilus)
    • 1N53 (the T-box antiterminator RNA) PubMed
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications