HtrC

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  • Description: similar to serine protease HtrA

Gene name yyxA
Synonyms yycK
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: yyxA
MW, pI 42 kDa, 5.315
Gene length, protein length 1200 bp, 400 aa
Immediate neighbours yyzO, walJ
Sequences Protein DNA DNA_with_flanks
Genetic context
YyxA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YyxA expression.png















Categories containing this gene/protein

proteolysis, sporulation proteins, membrane proteins

This gene is a member of the following regulons

SigG regulon

The gene

Basic information

  • Locus tag: BSU40360

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase S1B family (according to Swiss-Prot)
  • Paralogous protein(s): HtrA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

yyxA PubMed

  • Regulation: expressed during vegetative growth, repressed during stationary phase PubMed

yyxA transcript expressed during sporulation PubMed

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications

Elodie Marchadier, Rut Carballido-López, Sophie Brinster, Céline Fabret, Peggy Mervelet, Philippe Bessières, Marie-Françoise Noirot-Gros, Vincent Fromion, Philippe Noirot
An expanded protein-protein interaction network in Bacillus subtilis reveals a group of hubs: Exploration by an integrative approach.
Proteomics: 2011, 11(15);2981-91
[PubMed:21630458] [WorldCat.org] [DOI] (I p)

C Fabret, J A Hoch
A two-component signal transduction system essential for growth of Bacillus subtilis: implications for anti-infective therapy.
J Bacteriol: 1998, 180(23);6375-83
[PubMed:9829949] [WorldCat.org] [DOI] (P p)