Frr

• Description: ribosome recycling factor
  
  

Gene name	frr
Synonyms
Essential	yes PubMed
Product	ribosome recycling factor
Function	translation
Gene expression levels in SubtiExpress: frr
Metabolic function and regulation of this protein in SubtiPathways: frr
MW, pI	20 kDa, 5.329
Gene length, protein length	555 bp, 185 aa
Immediate neighbours	pyrH, uppS
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation, essential genes

This gene is a member of the following regulons

stringent response

The gene

Basic information

• Locus tag: BSU16520

Phenotypes of a mutant

essential PubMed

Database entries

• BsubCyc: BSU16520

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: RRF family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU16520

• Structure:

• UniProt: P81101

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: frr PubMed

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Christine Eymann, Georg Homuth, Christian Scharf, Michael Hecker
Bacillus subtilis functional genomics: global characterization of the stringent response by proteome and transcriptome analysis.
J Bacteriol: 2002, 184(9);2500-20
[PubMed:11948165] [WorldCat.org] [DOI] (P p)