YkuP

• Description: flavodoxin, binds FMN, replaces ferredoxin under conditions of iron limitation
  
  

Gene name	ykuP
Synonyms
Essential	no
Product	flavodoxin
Function	electron transfer
Gene expression levels in SubtiExpress: ykuP
Interactions involving this protein in SubtInteract: YkuP
Metabolic function and regulation of this protein in SubtiPathways: ykuP
MW, pI	20 kDa, 4.098
Gene length, protein length	534 bp, 178 aa
Immediate neighbours	ykuO, ykuQ
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

electron transport/ other

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

• Locus tag: BSU14170

Database entries

• BsubCyc: BSU14170

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: flavodoxin-like domain (according to Swiss-Prot)

• Paralogous protein(s): YkuN

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors: FMN

• Effectors of protein activity:

• Interactions:
  • YkuP-BioI PubMed
  • YjiB-YkuP PubMed
  • Des-YkuP (electron transfer to Des) PubMed

• Localization:

Database entries

• BsubCyc: BSU14170

• Structure:

• UniProt: O34589

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ykuN-ykuO-ykuP PubMed

• Expression browser: ykuP PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced upon iron starvation (Fur) PubMed
  • repressed by casamino acids PubMed
  • expressed under anaerobic conditions (ResD) PubMed
  • induced by nitric oxide under anaerobic conditions (NsrR) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed
  • ResD: transcription activation PubMed
  • NsrR: transcription repression PubMed

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 4675 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 1156 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: