CcpA regulon

Regulator	CcpA
Overview on the regulons (wiki page) Overview on the regulons (Excel file)

Genes in this regulon

Activation

• ackA
• ilvB-ilvH-ilvC-leuA-leuB-leuC-leuD
• pta

Repression

• abbA-ykuL-ccpC
• abn2
• acoA-acoB-acoC-acoL
• acoR-sspH
• acsA
• acuA-acuB-acuC
• amyE
• araA-araB-araD-araL-araM-araN-araP-araQ-abfA
• araE
• bglP-bglH
• bglS
• cccA
• cimH
• citM-yflN
• citZ-icd-mdh
• cstA
• ctaC
• cwlS
• cydA-cydB-cydC-cydD
• dctP
• dra-nupC-pdp
• fadB
• galK-galT
• glpD
• glpF-glpK
• glpTglpQ
• gmuB-gmuA-gmuC-gmuD-gmuR-gmuE-gmuF-gmuG
• gntR-gntK-gntP-gntZ
• hutP-hutH-hutU-hutI-hutG-hutM
• iolA-iolB-iolC-iolD-iolE-iolF-iolG-iolH-iolI-iolJ
• kdgR-kdgK-kdgA-kdgT
• kduI-kduD
• lcfA
• ldt
• levD-levE-levF-levG-sacC
• licB-licC-licA-licH
• malA-glvR-malP
• mmgA-mmgB-mmgC-mmgD-mmgE-yqiQ
• yxkF-msmX
• nagA
• odhA-odhB
• pel
• phoP-phoR
• phrC
• phrE
• phrG
• qcrA
• rapF
• rbsR-rbsK-rbsD-rbsA-rbsC-rbsB
• resA-resB-resC-resD-resE
• rocG
• rsbV-rsbW-sigB-rsbX
• sacP-sacA-ywdA
• yxjC-scoA-scoB-yxjF
• sigL
• sucC-sucD
• treP-treA-treR
• uxaC-yjmB-yjmC-yjmD-uxuA-yjmF-exuT-exuR-uxaB-uxaA
• xylA
• xylB
• xynB
• xynP
• yesM
• yfkN
• yhaR
• ylbP
• yobO
• yopL
• yozM
• ypiF
• yqxI
• yttP
• yvcI
• yvmB
• yvnA

• yxiE

Important publications on the CcpA regulon

Andrzej T Lulko, Girbe Buist, Jan Kok, Oscar P Kuipers
Transcriptome analysis of temporal regulation of carbon metabolism by CcpA in Bacillus subtilis reveals additional target genes.
J Mol Microbiol Biotechnol: 2007, 12(1-2);82-95
[PubMed:17183215] [WorldCat.org] [DOI] (P p)

Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135] [WorldCat.org] [DOI] (P p)

M S Moreno, B L Schneider, R R Maile, W Weyler, M H Saier
Catabolite repression mediated by the CcpA protein in Bacillus subtilis: novel modes of regulation revealed by whole-genome analyses.
Mol Microbiol: 2001, 39(5);1366-81
[PubMed:11251851] [WorldCat.org] [DOI] (P p)

K Yoshida, K Kobayashi, Y Miwa, C M Kang, M Matsunaga, H Yamaguchi, S Tojo, M Yamamoto, R Nishi, N Ogasawara, T Nakayama, Y Fujita
Combined transcriptome and proteome analysis as a powerful approach to study genes under glucose repression in Bacillus subtilis.
Nucleic Acids Res: 2001, 29(3);683-92
[PubMed:11160890] [WorldCat.org] [DOI] (I p)

S Tobisch, D Zühlke, J Bernhardt, J Stülke, M Hecker
Role of CcpA in regulation of the central pathways of carbon catabolism in Bacillus subtilis.
J Bacteriol: 1999, 181(22);6996-7004
[PubMed:10559165] [WorldCat.org] [DOI] (P p)