Pta
Revision as of 09:40, 17 April 2014 by 134.76.70.252 (talk)
- Description: phosphotransacetylase
Gene name | pta |
Synonyms | ipa-88d, ywfJ |
Essential | no |
Product | phosphotransacetylase |
Function | overflow metabolism |
Gene expression levels in SubtiExpress: pta | |
Metabolic function and regulation of this protein in SubtiPathways: pta | |
MW, pI | 34 kDa, 4.649 |
Gene length, protein length | 969 bp, 323 aa |
Immediate neighbours | cysL, ywfI |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
carbon core metabolism, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU37660
Phenotypes of a mutant
Database entries
- BsubCyc: BSU37660
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Acetyl-CoA + phosphate = CoA + acetyl phosphate (according to Swiss-Prot)
- Protein family: phosphate acetyltransferase and butyryltransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation on (Ser-123 OR Thr-128 OR Ser-129) PubMed
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- BsubCyc: BSU37660
- UniProt: P39646
- KEGG entry: [3]
- E.C. number: 2.3.1.8
Additional information
Expression and regulation
- Operon: pta PubMed
- Regulation:
- expression activated by glucose (2.6 fold) (CcpA) PubMed
- Additional information:
Biological materials
- Mutant: GP668 (aphA3), available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Alan J Wolfe
The acetate switch.
Microbiol Mol Biol Rev: 2005, 69(1);12-50
[PubMed:15755952]
[WorldCat.org]
[DOI]
(P p)
Original publications
Additional publications: PubMed