YdfH

• Description: two-component sensor kinase, control of ydfJ expression
  
  

Gene name	ydfH
Synonyms
Essential	no
Product	two-component sensor kinase (NarL family)
Function	control of ydfJ expression
MW, pI	46 kDa, 9.598
Gene length, protein length	1221 bp, 407 aa
Immediate neighbours	ydfG, ydfI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU05410

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

protein modification, transcription factors and their control, membrane proteins, phosphoproteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of YdfI

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: 4 transmembrane segments

• Modification: autophosphorylation on a His residue

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YdfH-YdfI

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P96685

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ydfH-ydfI PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Masakuni Serizawa, Junichi Sekiguchi
The Bacillus subtilis YdfHI two-component system regulates the transcription of ydfJ, a member of the RND superfamily.
Microbiology (Reading): 2005, 151(Pt 6);1769-1778
[PubMed:15941986] [WorldCat.org] [DOI] (P p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)